inflammation

B Cells Found To Contribute To Sepsis

B cells, better known for producing antibodies, have now been found to also play an important role in the inflammatory response against bacterial toxins during sepsis.

Stone Man Syndrome Linked To Inflammation

Induced pluripotent stem cells have helped scientists uncover a new mechanism for the development of Stone Man Syndrome, narrowing down the search for much needed therapies.

New Gene Involved In Sepsis Found

A large-scale forward genetic screen has identified Gasdermin-D as a key mediator of the lethal septic shock response to bacteria.

GlycA: A Biomarker For Premature Death

High levels of the biomarker GlycA has been identified as a risk factor for premature death due to infection.

Early Clinical Trial Success For Rheumatoid Arthritis Vaccine

A small clinical trial has shown that a dendritic cell-based vaccine against citrullinated peptides could treat rheumatoid arthritis.

How Inflammation Switches Off Tregs

DBC1, which has recently been shown to decrease the stability of immune suppressing transcription factor FOXP3, could be a therapeutic target for autoimmune diseases.

Neural Circuits Linked To Excessive Coughing Exposed By Herpes

Fluorescent viral traces have helped identify the specific brain regions triggered during excessive coughing.

The Anti-Inflammatory Receptor Tag Team

Super resolution microscopy has revealed the receptors involved in IL-37 signaling, paving the way for new anti-inflammatory therapies.

A New Treatment For Inflammatory Diseases

The molecule MCC950 targets the inflammasomes and could be used to treat diseases such as cryopyrin-associated periodic syndromes.