10 ’Omics You Need To Know

Confused by the proliferation of ‘omics but don’t want to be left behind? Fret not, Asian Scientist Magazine has got you covered with our handy explainer on the hottest ‘omics around.


20160721 transcriptomics

Material studied: RNA
Methods used: Microarrays, RNA sequencing

For our genes to be expressed, cells must first transcribe (or copy) genomic DNA into RNA. The full range of RNA transcripts produced—the transcriptome—varies across different cell types, as well as between healthy and diseased states. Cancer cells, for example, show altered gene expression, as do cells infected with viruses and bacteria.

In transcriptomics, high-throughput methods such as microarray analysis and RNA sequencing are used to measure the levels of thousands of transcripts at a time, giving researchers a comprehensive overview of how changes in our gene expression may lead to or stem from disease.

Shuzhen received a PhD degree from the Johns Hopkins Bloomberg School of Public Health, USA, where she studied the immune response of mosquito vectors to dengue virus.

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