sepsis
Trapping Toxins to Prevent Sepsis
Researchers from Singapore have developed synthetic nanonets, which catch bacterial toxins and pro-inflammatory cytokine molecules, offering potential breakthroughs in sepsis treatment.
Bacterial Infection Stresses Blood Stem Cells
Bacterial infections can reduce the self-renewal capacity of hematopoietic stem cells in bone marrow, study says.
A Nanoscale Solution To Sepsis
Potent antioxidant nanoparticles that can mop up excess reactive oxygen species could help prevent sepsis-related deaths.
Deleting Enzymes Takes The Edge Off Septic Shock
Inhibiting IPMK enzymes could help dampen the overexuberant immune response during sepsis, a leading cause of death from infections.
Measuring The ‘Springiness’ Of Red Blood Cells
A microfluidic method of measuring red blood cell deformity has revealed that the cells take longer to recover if they are constricted for more than three minutes.
Breaching The Brain To Treat Septic Shock
A neuropeptide called orexin has been shown to prevent mice from dying from septic shock.
B Cells Found To Contribute To Sepsis
B cells, better known for producing antibodies, have now been found to also play an important role in the inflammatory response against bacterial toxins during sepsis.
An Antibody Approach To Preventing Sepsis
Research in mice suggests that a new antibody-based therapy could be a valuable weapon in the battle against sepsis.
New Gene Involved In Sepsis Found
A large-scale forward genetic screen has identified Gasdermin-D as a key mediator of the lethal septic shock response to bacteria.
Viral Protein That Triggers Dengue Shock Identified
The discovery that NS1 triggers vascular leakage via TLR4 suggests that drugs against bacterial sepsis could be repurposed to treat dengue.
