crispr cas9

7 Must-Read Stories In May 2018

Prominent personalities, therapies for HIV infection and cool feats of engineering were topics of interest in the month of May.

Gene Editing Blocks HIV Transmission In Cells

Researchers have used gene editing to block the replication of HIV in human cells.

CRISPR Screening Identifies Important Tumor Suppressor Genes

Using gene editing to systematically screen a large number of tumor suppressor genes, researchers in China have identified five genes linked to lung tumor growth.

Gene-Edited Pigs Better Model Huntington’s Disease

Using the CRISPR/Cas9 gene editing system, researchers have developed a pig model of Huntington’s disease that better mimics how the disease progresses in humans.

Hiding Gene Editing From The Immune System

By using a phosphatase to remove a chemical group on synthetic guide RNAs, scientists in South Korea have made CRISPR-Cas9 less immunogenic and less toxic.

Making Gene Editing More Precise

Scientists at Osaka University in Japan have developed a modified Cas9 enzyme that greatly suppresses the rate of unintended genetic mutation compared to conventional methods.

CRISPR Caught In The Act

Using high-speed atomic-force microscopy, scientists in Japan have observed how the CRISPR/Cas9 complex cuts DNA in real-time.

Targeted Delivery Of CRISPR Into Bone Tumors

Scientists in Hong Kong have developed a method to carry the CRISPR/Cas9 gene editing system into bone tumors, thus enabling therapeutic gene editing.

Making Pigs Leaner Through CRISPR

Using CRISPR/Cas gene-editing, scientists in China have introduced a gene into pigs that makes them lean and cold-resistant.