10 Unsolved Questions In Neuroscience

The mind still holds many mysteries today. Here, we uncover what we know about ten of them.

AsianScientist (Jan. 26, 2016) – Due to its incredible complexity, the brain is an immensely challenging subject of study. The average human brain has about 90 billion neurons that make 100 trillion connections or synapses. Scientists believe this staggering number of neurons is responsible for the traits that make us uniquely human: our thoughts, memories and emotions.

Recent technological advances in functional magnetic resonance imaging, optogenetics and whole brain imaging have made the brain accessible in a way that previous generations of neuroscientists could only dream of. But techniques alone will not get us far; they need to be put in the service of good research questions.

This issue, we pick ten unsolved questions in neuroscience that are likely to captivate scientists of this generation. While some of these questions seem more philosophical than scientific, remember that PhDs are after all doctors of philosophy!


1. How is information encoded by neurons?

The brain has often been likened to a computer. In essence, both follow the same basic principles: electrical inputs arrive in the brain, which are then processed before leaving as electrical outputs. While computers encode information in a binary fashion, much less is known about how neurons encode information.

What we do know is that neurons conduct electrical impulses down specialized extensions known as axons, before releasing chemical signals to neighboring neurons at junctions called synapses. These electrical and chemical signals carry information about everything we see, hear, taste and touch.

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Ying Ying completed her PhD in neurobiology at the University of Basel, where she studied the role of bone morphogenetic protein in structural plasticity of neurons.

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