AsianScientist (Dec. 4, 2013) – A global study reveals a pandemic of intolerable pain affecting billions, caused by over-regulation of pain medicines.
The ground-breaking international collaborative survey, published in Annals of Oncology, shows that more than half of the world’s population live in countries where regulations that aim to stem drug misuse leave cancer patients without access to opioid medicines for managing cancer pain.
Results from the Global Opioid Policy Initiative (GOPI) project show that more than four billion people live in countries where regulations leave cancer patients suffering excruciating pain. National governments must take urgent action to improve access to these medicines, says the European Society for Medical Oncology (ESMO), leader of a group of 22 partners that have launched the first global survey to evaluate the availability and accessibility of opioids for cancer pain management.
“The GOPI study has uncovered a pandemic of over-regulation in much of the developing world that is making it catastrophically difficult to provide basic medication to relieve strong cancer pain,” said Nathan Cherny, chair of the ESMO Palliative Care Working Group and lead author of the report.
“Most of the world’s population lacks the necessary access to opioids for cancer pain management and palliative care, as well as acute, post-operative, obstetric and chronic pain.”
The study, conducted in Africa, Asia, Latin America & the Caribbean and the Middle East, assessed the availability of the seven opioid medications considered to be essential for the relief of cancer pain by the WHO Model List of Essential Medicines and the International Association for Hospice and Palliative Care. Those essential medications include codeine, oral oxycodone, transdermal fentanyl, immediate and slow release oral morphine, as well as injectable morphine, and oral methadone.
While there are problems with the supply of these medicines in many countries, the main problem is over-regulation that makes it difficult for healthcare professionals to prescribe and administer them for legitimate medical use, the authors added.
“This is a tragedy born out of good intentions,” said Cherny. “When opioids are over-regulated, the precautionary measures to prevent abuse and diversion are excessive and impair the ability of healthcare systems to relieve real suffering. The GOPI study has uncovered over-regulation in much of the developing world.”
The next step is for international and local organizations working alongside governments and regulators to thoughtfully address the problems, said study co-author James Cleary.
“Regulatory reform must be partnered with education of healthcare providers in the safe and responsible use of opioid medication, education of the public to destigmatize opioid analgesics and improved infrastructure for supply and distribution,” he said.
The article can be found at: Cherny N et al. (2013) The Global Opioid Policy Initiative (GOPI) project to evaluate the availability and accessibility of opioids for the management of cancer pain in Africa, Asia, Latin America and the Caribbean, and the Middle East: introduction and methodology.
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Source: European Society for Medical Oncology; Photo: Lel4nd/Flickr/CC.
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