innate immunity
How Bats Can Carry Viruses Without Getting Sick
Scientists in Singapore have discovered that a subdued immune response may be the reason why bats can harbor deadly viruses without batting an eyelid.
How The Immune System Spots Melioidosis Bacteria
Researchers have found that cell fusion—rather than the bacteria itself—is what alerts the immune system to Burkholderia pseudomallei infection.
Hiding Gene Editing From The Immune System
By using a phosphatase to remove a chemical group on synthetic guide RNAs, scientists in South Korea have made CRISPR-Cas9 less immunogenic and less toxic.
Deleting Enzymes Takes The Edge Off Septic Shock
Inhibiting IPMK enzymes could help dampen the overexuberant immune response during sepsis, a leading cause of death from infections.
How Hepatitis C Escapes Our Immune System
The hepatitis C NS3 protein plays an important role in subverting the host immune response to establish a chronic infection, scientists say.
Mini-Pig Study: Inflammation May Drive Diabetic Kidney Injury
A study in pigs has uncovered the mechanistic link between diet, diabetes and kidney failure.
DNA-TLR9 Zipper Triggers Autoimmune Response
A zipper-like arrangement of DNA can bind strongly to the receptor TLR9 and trigger a strong immune response.
TLR9: Two Rings To Bind Them?
The structure of TLR9 could lead to the design of new drugs targeting this important immune receptor.
