garvan institute of medical research
Will You Break A Bone Due To Osteoporosis? It’s In Your Genes
Predicting an individual’s risk of osteoporosis-related fractures becomes much more accurate when taking genetic factors into account alongside clinical factors.
How Improve Genomic Analysis? Attach Some Sequins
Called sequins, these synthetic human genome sequences can help researchers optimize how gene sequencing is carried out.
Neutrophils Discriminate Between Infected & Sterile Injuries
A new technique to label neutrophils shows that they re-locate to the lymph nodes and activate adaptive immunity only if bacteria are present at the site of injury.
When B Cells Go Rogue
Inactivation of the death receptor FAS allows rogue B cells to escape antigen control and drive autoimmunity.
Found: Critical Regulator Of Unconventional Immune Cells
By studying patients lacking STAT3, researchers have identified the protein as essential for innate-like immune cells known as NKT and MAIT cells.
A Switch That Could Tame The Most Aggressive Breast Cancer
Researchers propose that blocking a gene called ID4 could make triple-negative breast cancers more responsive to treatment.
Redefining The Genetic Landscape Of Pancreatic Cancer
Classifying pancreatic cancer into four subtypes based on whole genome sequencing could help improve the specificity of existing treatments.
The ‘Frankenstein’ DNA Of Cancer Cells
Giant neochromosomes found in certain cancers are stitched together from fragments formed after catastrophic chromosomal 'explosions'.
New Anti-Tumor Properties Of Old Bone Drugs
Drugs currently used to treat osteoporosis could also be used to treat soft tissue cancers, scientists say.
Detecting Pancreatic Cancer Early
A study of 766 pancreatic cancer patients suggests that there are genetic factors driving the disease.
