mechanobiology

Sensing Tension In The Plasma Membrane

The membrane-bending protein FBP17 has been identified as a sensor of cell surface tension that can regulate cell migration through actin polyermization.

The Surprising Origins Of Cellular Handedness

The orientation of actin protein in the cytoskeleton can determine the asymmetry of the entire cell.

The Wound Healing Tug-Of-War

Tension is not always bad. Scientists have now shown that it is a necessary part of wound healing, especially where the underlying ECM has been damaged.

How α-Catenin Converts Force Into Biochemical Signals

Magnetic tweezers have allowed scientists to unravel what happens when α-catenin is stretched.