mechanobiology institute

Why Embryos Die Without GPIs

A study in nematode worms shows that glycosylphosphatidylinositol lipid anchors are essential for membrane stability, particularly during embryogenesis.

From Periphery To The Nucleus

A previously unidentified perinuclear actin ring could be the link between mechanosensing at the cell periphery and DNA regulation in the nucleus.

Microfabricated Mirrors For 3D Super-Resolution Microscopy

Microfabricated mirror wells could help turn ordinary inverted microscopes into super-resolution, 3D imagers.

The Surprising Origins Of Cellular Handedness

The orientation of actin protein in the cytoskeleton can determine the asymmetry of the entire cell.

The Wound Healing Tug-Of-War

Tension is not always bad. Scientists have now shown that it is a necessary part of wound healing, especially where the underlying ECM has been damaged.

Mapping The Cell Adhesion Network

Taking a quantitative approach, researchers have resolved the complexity the E-cadherin interactome.

How α-Catenin Converts Force Into Biochemical Signals

Magnetic tweezers have allowed scientists to unravel what happens when α-catenin is stretched.

The Physics Of Wound Healing

Experimental and computational evidence points to a third mechanism of wound healing previously unknown to science.