immunology

TLR9: Two Rings To Bind Them?

The structure of TLR9 could lead to the design of new drugs targeting this important immune receptor.

The Secrets Of Skin-Based Immunity

Scientists have resolved the decades old mystery of what activates the immune receptor CD1a: lipids.

Putting The Brakes On Inflammation

The protein MST4 has been shown to protect mice from septic shock by dampening inflammation.

Ubiquitination The Missing Link In The STING Pathway

Poly-ubiquitination links the key microbial DNA detector STING with downstream effects, study shows.

Australia’s US$34 Million Center For Immune Visualization

The ARC Center of Excellence in Advanced Molecular Imaging will help to answer how single molecules function in the context of immune cells.

Got Celiac Disease? Have Some Hookworms!

Hookworms could help celiac disease patients increase their tolerance to gluten, study shows.

How Plague Remodels The Lymph Nodes

The ancient scourge of bubonic plague has provided researchers with new insights on how the body responds to infections.

PTX3 Protects The Host From Histones

Scientists have found a surprising way that PTX3 can help mitigate sepsis: by directly binding to and thereby removing extracellular histones.

Immune-Brain Interaction Links Stress To Depression

The immune system, in particular a receptor called TLR4, could form the link between stress and depression.