epigenetics

Premature Aging Syndrome Caused By Chromatin Chaos

A human stem cell model of Werner syndrome has linked premature aging to the deterioration of heterochromatin.

DNA Methylation Regulates Longevity In Humans

A genome wide association study has uncovered differentially methylated regions linked to longevity and the suppression of age-related diseases.

Epigenetic Marks Affect Children’s Brain Development

Methylation of the HES1 gene in the womb can influence a child's later cognitive development, scientists say.

Not Junk: lncRNA Linked To Anxiety In Mice

The long non-coding RNA Gomafu has been linked to anxiety-like behaviors and could help the brain respond to environmental changes.

The Epigenetic Regulator Of Bone Formation

JMJD3 cooperates with the master regulator RUNX2 to control cartilage ossification into bone, study shows.

DNA Methylation Indicates Accelerated Aging

A study of 5,000 elderly people has found that a DNA modification known as methylation can impact the aging process.

Studying Muscle Loss With Worms In Space

The roundworm Caenorhabditis elegans could tell us about the effects of microgravity on muscle and bone.

Kyowa Hakko Kirin & Syndax To Develop Tumor Therapy

Entinostat, an epigenetic modification drug, is slated for clinical trials in Japan and Korea in 2015.

The Dual Role Of Histone Acetylation In Stem Cells

The H3K9Ac epigenetic mark has contrasting effects at different stages of stem cell differentiation, study shows.