circadian rhythm

Melatonin Suppresses Activity Of Brain Tumor Stem-Like Cells

The ‘sleep hormone’ melatonin directly targets stem-like cells of glioblastomas by altering their biology and inhibiting their ability to multiply.

Circadian Genes Help Predict Mood Changes In Bipolar Mice

Genes controlling the circadian rhythm could be closely linked to mood change-like behaviors associated with bipolar disorder, scientists say.

RaQualia & Nagoya’s ITbM To Develop Circadian Rhythm Drugs

The academia-industry partnership is hoped to yield small molecule drugs that can treat symptoms of circadian clock disruption.

Keeping The Circadian Clock Stable, Whatever The Temperature

Scientists have proposed a phosphoswitch mechanism to explain the stability of the key circadian protein PER2 in the face of fluctuating temperatures.

Female Fertility Linked To Circadian Cycle

A study in mice suggests that the age-related decline in fertility can be mitigated with good ‘circadian hygiene.’

The Tiny Protein That Syncs With The Earth’s Rotation

Oscillations of a 10 nm protein help cells keep in tune with the 24 hour cycles of the Earth.

Tweaking Circadian Rhythms With Small Molecule Drugs

Synthetic chemistry has enabled researchers to develop small molecule drugs which target regulators of the circadian cycle.

Pinpointing The Pacemaker Cells Of Sleep Cycles

A study in mice has identified the specific neurons involved in the regulation of the circadian cycle.