Tracking COVID-19 Through Wastewater

Researchers have suggested tracking the presence of SARS-CoV-2 in wastewater to monitor the spread of COVID-19 in communities.

AsianScientist (Jul. 14, 2020) – Wastewater could be used as a surveillance tool to monitor the invasion, spread and eradication of COVID-19 in communities, suggest the authors of a review published in Science of the Total Environment.

SARS-CoV-2, the virus that causes COVID-19, is mainly spread through the inhalation of aerosol or contact with contaminated surfaces. However, there is growing evidence of gastrointestinal symptoms such as diarrhea amongst COVID-19 patients, and genetic material from the virus has been found not only in patients’ feces but also in wastewater.

“The presence of SARS-CoV-2 genetic material in wastewater provides an opportunity to monitor the spread of COVID-19 in a community. Although wastewater is not widely used as a disease surveillance tool, it is starting to gain some traction,” said Assistant Professor Masaaki Kitajima, an environmental engineer at Hokkaido University and first author of the study.

According to Kitajima and his team, using wastewater to monitor COVID-19 offers several advantages over other methods, such as clinical testing. It can detect low levels of virus particles and detect the virus when patients are asymptomatic, meaning it could provide an early warning system for new outbreaks or resurgence in communities. It could be especially useful in developing countries where clinical diagnosis and reporting systems may be limited, making it easier to make fair comparisons between countries.

Wastewater monitoring could help detect genetic variation between circulating strains in different regions, enabling scientists to monitor the evolution of the virus genome over time. It could also be used to see whether infections have decreased as a result of public health interventions such as lockdown, social isolation and social distancing.

However, the authors also highlight several challenges for wastewater monitoring.

“Although multiple efforts are underway to develop environmental surveillance programs for SARS-CoV-2, there are gaps in our knowledge and further research is needed before we can reliably use wastewater to monitor COVID-19 outbreaks,” said Kitajima.

One major challenge is the absence of a standardized protocol for monitoring SARS-CoV-2 in wastewater. Detecting viral genetic material in wastewater requires a virus concentration step to enable extraction and detection, but there is limited knowledge on how to do this efficiently for SARS-CoV-2.

To evaluate human health risks, it is also crucial to know how the virus decays in water environments. At present, the stability of the SARS-CoV-2 genome in wastewater is largely unknown. In addition, it is still unknown whether aerosols from wastewater can contain the virus and be a potential health risk for workers at wastewater treatment plants.

“The use of national and international wastewater surveillance campaigns could provide a better understanding of the spread of the COVID-19 and aid the decision making of public health officials, but further research is needed before wastewater monitoring for SARS-CoV-2 can be widely used,” the researchers concluded.

The article can be found at: Kitajima et al. (2020) SARS-CoV-2 in Wastewater: State of the Knowledge and Research Needs.


Source: Hokkaido University; Photo: National Institute of Allergy and Infectious Diseases.
Disclaimer: This article does not necessarily reflect the views of AsianScientist or its staff.

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